There are usually pretty good explanations of the results in the online help. Start by looking under help/results, or by using Help/What's this on once of the results.
As far as the clamp force results, This is dependent on two things, the projected area in the Z axis and the pressure to fill. If the die draw of your part is not oriented to match the Z axis in Adviser, you will not get accurate clamp force results. Did you only used a single cavity for the Moldflow analysis compared to two cavities for your internal program?
The Temperature variance and Cooling time variance show the variation from the average. That's how negative numbers are possible. My pet peeve has been that the software will not give you the average that it is varying from. For actual cooling times, go to the Quality Prediction plot and use the traffic light and examine result commands. This will give you a Time to reach ejection temperature result.