If you describe what it is and what you want to simulate, you may get more replies from people who know CFD well but not what Peltier device is 🙂
OJ
Peltier device is also known as a TEC thermal electric cooler. It is a heat pump that pushes heat between two ceramic plates when current is present. I have a system comprised of part to be heated, Peltier device, and heat sink. I would like to know how temperature of the part is changing when different current is applied. In the past BRNI was considering developing this feature in CFDesign but I am not sure if it was ever implemented.
Simple answer: Yes. Take a look in the Materials section, you will find TEC's