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At first glance I'd suggest reinstalling .NET. The Ribbon uses Microsoft .NET and Windows Presentation Foundation (WPF). If there is a problem with these the error you are getting might be caused by that.
Then it might be something else:
- Are you getting any specific error messages? Can you provide details or screen shots?
- Are there any Windows Application Event Logs for this crash?
- Are you starting it as the user who installed AutoCAD Mechanical and Inventor?
- What if you try and launch the application from another user?
- Was the application installed when background applications and antivirus applications were stopped?