James,
Iusr_machinemane is already present, but it didnot work.
So I added "Everyone" and granted "local activation"..
It worked, thank you very much.
I have another win2003 machine, installed Mapguide 6.0 and it is working fine . I did not change anything in DCOMCnfg , but it is working fine..
I appreciate your support..
thanks
Ram