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When installing:
- Disable UAC
- Make certain you are an Administrator
- Try installing from Diagnostic mode
- Some customers have reported that it may need several reinstalls.
It sounds like you might have multiple versions of AutoCAD 2010 installed and may need to make some choices.
AutoCAD Civil 3D 2010 is only available in 32-bit. Therefore it requires the 32-bit AutoCAD Raster Design Object Enabler. If you later install the 64-bit OE it will over write the 32-bit OE. Meaning you cannot have both the 32-bit and 64-bit versions of the OE.
If you have other versions of AutoCAD 2010 you will need to choose which versions you want the IOE to work with; the 32-bit versions of AutoCAD (Civil 3D) or the 64-bit versions of AutoCAD. Then install the OE for the bits of the host AutoCAD that you most need the OE for. Most need it for Civil 3D so consider installing the 32-bit OE.
Douglas Lauritsen, Autodesk Product Support