You can slope pipe 2 ways prior to routing you can activate the slope panel on the 3D Piping Home Ribbon this will slope horizontal pipe per the specified ratio.
The second can also slope pipe after it has been already routed by using the command PLANTPIPESLOPE. This will allow you to slope a selected route with multiple segments and enter a common slope. Choose the starting pipe segment then the last pipe segment even if its across multiple piping fittings and other pipe segments.
Mike G (Autodesk)
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