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I'm not having any luck with databases either. I just installed Civil3D 2012 on Windows 7 64-bit.
Create new ODBC connection.. FAIL
I even tried it on my 32-bit installation... NOPE!
I guess the process of connecting to .mdb just wasn't complicated enough.
64 bit requires a Microsoft Access Driver
You may need to download from Microsoft
Then you just need to create a new Data Source (in Control Panel -> Data Sources -> ODBC Data Source Administrator)
Check this out for more info:
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