The keynotes feature is an AutoCAD Architecture feature (like walls) that MEP inherits. The default keynotes are Architectural. So not many MEP users, use this feature. I am not aware of a way to keep it open. You should re-post this question in the AutoCAD Architecture forum where you will have users with more experience with this feature. They may have some tricks that I am not aware of. And if it cannot be done, consider posting a suggestion at the feedback site here.
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