Your wheel "should" zoom in AutoCAD without holding the shift key. That is
normally default behavior. I suspect, like you say, it's a mouse driver
setting. You should be able to edit what the buttons do. Make sure that
the wheel setting is not something weird. just normal scrolling should be
fine.
The transparent orbit command you're getting is default as well. This can
be chnaged in the CUI. You'll find it in the mouse buttons area under shift
click.
Matt