I have AutoCAD Architecture 2012 64 bit installed on my Windows 8 machine and it is running just fine. You might have some user account control settings but they can be tweaked to work. (I don't know which ones.) The only issue I have seen is that when exiting AutoCAD it will send a report to Autodesk (nearly every time). I have also noticed that upon exit I have recieved a couple of "Fatal Errors". However to date I have yest to lose any information as it does what I want and then crashes on exit. Neither has happened today but that doesn't mean it won't.