In Options > Files > Template Settings > Default Template File name for QNEW, Browse to your default template and select it. This will always be the template file your system uses when you first start the program or click the QNEW button above the Ribbon. If you ever want to use a different template go to the Application Menu and click New or type NEW at the command line.
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@ Pendean I think he wants to set a template file for every time he opens AutoCAD it opens and you don't have to go searching for it every time. Your suggestion creates more work. The point is to set it up so you don't have to keep looking for your "shortcut".
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